CACYBP cDNA

cDNA

CACYBP is primarily a nuclear protein that contains one CS domain and one SGS domain. It is believed to be involved in calcium-dependent ubiquitination and subsequent proteosomal degradation of target proteins. It most likely serves as a molecular bridge in ubiquitin E3 complexes. It also participates in the ubiquitin-mediated degradation of beta-catenin. CACYBP is thought to be a potential inhibitor of cell growth and invasion in the gastric cancer cell through its effects on beta-catenin protein expression and transcriptional activation of TCF/LEF.

Human

606186

558bp

1. Centrifuge at 7000rpm for 1 minute.; ; 2. Carefully open the vial and add 100ul of sterile water to dissolve the DNA.; ; Each tube contains approximately 10ug of lyophilized plasmid.

MQQKSQKKAE LLDNEKPAAV VAPITTGYTV KISNYGWDQS DKFVKIYITL TGVHQVPTEN VQVHFTERSF DLLVKNLNGK SYSMIVNNLL KPISVEGSSK KVKTDTVLIL CRKKVENTRW DYLTQVEKEC KEKEKPSYDT ETDPSEGLMN VLKKIYEDGD DDMKRTINKA WVESREKQAK GDTEF

ATGCAACAGA AATCACAGAA GAAAGCAGAA CTTCTTGATA ATGAAAAACC AGCTGCTGTG GTTGCTCCCA TTACAACGGG CTATACGGTG AAAATCAGTA ATTATGGATG GGATCAGTCA GATAAGTTTG TGAAAATCTA CATTACCTTA ACTGGAGTTC ATCAAGTTCC CACTGAGAAT GTGCAGGTGC ATTTCACAGA GAGGTCATTT GATCTTTTGG TAAAGAATCT AAATGGGAAG AGTTACTCCA TGATTGTGAA CAATCTCTTG AAACCCATCT CTGTGGAAGG CAGTTCAAAA AAAGTCAAGA CTGATACAGT TCTTATATTG TGTAGAAAGA AAGTGGAAAA CACAAGGTGG GATTACCTGA CCCAGGTTGA AAAGGAGTGC AAAGAAAAAG AGAAGCCCTC CTATGACACT GAAACAGATC CTAGTGAGGG ATTGATGAAT GTTCTAAAGA AAATTTATGA AGATGGAGAC GATGATATGA AGCGAACCAT TAATAAAGCC TGGGTGGAAT CAAGAGAGAA GCAAGCCAAA GGAGACACGG AATTTTGA