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Rabbit antibody to M6PR

Rabbit antibody to M6PR

ArtNr	OSM00062G
Hersteller	Osenses
Menge	500ug
Kategorie	Oncology Antibodies By Cell Type Carcinoma Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host	Rabbit
Isotype	IgG
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr
Similar products	M6pr, CD-MPR, Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptor, MPR 46, 46mpr
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Also known	CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr
Target	FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex. SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3. SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.
Spcs X-react.	Mouse, rat, human, marmoset. Other species not yet tested.
Applications info	IHC, WB. Use at a concentration of 10-50 ug/ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Ludwig T, et al. J. Biol. Chem. 267:12211-12219(1992).
Limitation	For research use only
Immunogen	A synthetic peptide from mouse M6PR conjugated to blue carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/P24668 http://www.uniprot.org/uniprot/Q6AY20 http://www.uniprot.org/uniprot/P20645
Purity	IgG
Clonality	Polyclonal
Specificity	Specific for MPRD.
Format	Lyophilised
Reconstitution	Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 500ug

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Lieferung vsl. bis 16.10.2025

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