Vergleich

Rabbit antibody to M6PR

ArtNr OSM00062G
Hersteller Osenses
Menge 500ug
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus), Monkey (Cynomolgus, Simian)
Host Rabbit
Isotype IgG
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr
Similar products M6pr, CD-MPR, Cation-dependent mannose-6-phosphate receptor, CD Man-6-P receptor, 46 kDa mannose 6-phosphate receptor, MPR 46, 46mpr
Lieferbar
Also known
CD Man-6-P receptor, CD-MPR, 46 kDa mannose 6-phosphate receptor, MPR 46, Cation-dependent mannose-6-phosphate receptor, M6pr, 46mpr
Target
FUNCTION: Transport of phosphorylated lysosomal enzymes from the Golgi complex and the cell surface to lysosomes. Lysosomal enzymes bearing phosphomannosyl residues bind specifically to mannose-6-phosphate receptors in the Golgi apparatus and the resulting receptor-ligand complex is transported to an acidic prelyosomal compartment where the low pH mediates the dissociation of the complex.
SUBUNIT: Homodimer. Binds GGA1, GGA2 and GGA3.
SUBCELLULAR LOCATION: Lysosome membrane; Single-pass type I membrane protein.
Spcs X-react.
Mouse, rat, human, marmoset. Other species not yet tested.
Applications info
IHC, WB. Use at a concentration of 10-50 ug/ml. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Ludwig T, et al. J. Biol. Chem. 267:12211-12219(1992).
Limitation
For research use only
Immunogen
A synthetic peptide from mouse M6PR conjugated to blue carrier protein was used as the antigen.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/P24668
http://www.uniprot.org/uniprot/Q6AY20
http://www.uniprot.org/uniprot/P20645
Purity
IgG
Clonality
Polyclonal
Specificity
Specific for MPRD.
Format
Lyophilised
Reconstitution
Reconstitute in 500 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500ug
Lieferbar: In stock
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