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Rabbit antibody to Complexin-2 (40-80)

Rabbit antibody to Complexin-2 (40-80)

ArtNr	OSC00178W
Hersteller	Osenses
Menge	100ul
Kategorie	Neuroscience Molecular Targets for Neuroscience Antibodies Immunohistochemistry Western Blot Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	CPLX2, Complexin II, CPX II, Synaphin-1, Complexin 2
Similar products	CPLX2, Complexin 2, Complexin II, CPX II, Synaphin-1
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Also known	CPLX2, Complexin II, CPX II, Synaphin-1, Complexin 2
Target	FUNCTION: Positively regulates a late step in synaptic vesicle exocytosis. Also involved in mast cell exocytosis. SUBCELLULAR LOCATION: Cytoplasm a€C cytosol. Note: Enriched at synaptic-releasing sites in mature neurons. Tissue specificity: Nervous system. In hippocampus and cerebellum, expressed mainly by excitatory neurons. Down-regulated in brain cortex from patients suffering from Huntington disease, bipolar disorder or major depression. Down-regulated in cerebellum from patients with schizophrenia.
Spcs X-react.	Mouse, rat, human. Other species not yet tested.
Applications info	IHC, WB. A dilution of 1 : 3000 to 1 : 4000 is recommended for WB and 1:1000 to 1:2000 for IHC-P. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. McMahon H.T, et al. Cell 83:111-119(1995) 2. Ota T, et al. Nat. Genet. 36:40-45(2004)
Limitation	For research use only
Immunogen	A synthetic peptide from aa region 40-80 of human Complexin-2 conjugated to blue carrier protein was used as the antigen. The peptide is homologous in rat and mouse.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/Q6PUV4 http://www.uniprot.org/uniprot/P84086 http://www.uniprot.org/uniprot/P84087
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for Complexin-2.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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