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Rabbit antibody to SMURF1

Rabbit antibody to SMURF1

ArtNr	OSS00234W
Hersteller	Osenses
Menge	100ul
Kategorie	Neuroscience Aging & Neurological Disorders Antibodies Cell Biology Cell Status Immunohistochemistry Western Blot Autophagy Primary Antibodies
Typ	Antibody Polyclonal
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Alias	SMUF1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1
Similar products	SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1, SMUF1
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Also known	SMUF1, SMAD ubiquitination regulatory factor 1, SMAD-specific E3 ubiquitin-protein ligase 1
Target	Function: E3 ubiquitin-protein ligase which accepts ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. Interacts with receptor-regulated SMADs specific for the BMP pathway, SMAD1 and SMAD5, in order to trigger their ubiquitination and degradation and hence their inactivation.
Spcs X-react.	Human, rat, mouse. Other species not yet tested.
Applications info	IHC, WB. A dilution of 1: 300 to 1 : 2000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage	Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date	12 months after reconstitution
Shipping	This item will be shipped to you at ambient temperature in a lyophilised form.
References	1. Carninci P, et al. Science 309:1559-1563(2005) 2. Nagase T, et al. DNA Res. 7:273-281(2000) 3. Hillier L.W, et al. Nature 424:157-164(2003)
Limitation	For research use only
Immunogen	A synthetic peptide from internal region of mouse E3 ubiquitin protein ligase SMURF1 conjugated to an immunogenic carrier protein was used as the antigen.
Conjugate	Unconjugated antibody
Accession	http://www.uniprot.org/uniprot/Q9HCE7 http://www.uniprot.org/uniprot/D3ZCF5 http://www.uniprot.org/uniprot/Q9CUN6
Purity	Whole serum
Clonality	Polyclonal
Specificity	Specific for SMUF1.
Format	Lyophilised
Reconstitution	Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100ul

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