Vergleich

Rabbit antibody to KCNT1

ArtNr OSP00131W
Hersteller Osenses
Menge 100ul
Kategorie
Typ Antibody Polyclonal
Applikationen WB, IHC
Specific against Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host Rabbit
ECLASS 10.1 32160702
ECLASS 11.0 32160702
UNSPSC 12352203
Alias Potassium channel subfamily T member 1, KCa4.1, SLACK
Similar products KCa4.1, SLACK, Potassium channel subfamily T member 1
Lieferbar
Also known
Potassium channel subfamily T member 1, KCa4.1, SLACK
Target
FUNCTION: Testis-specific potassium channel activated by both intracellular pH and membrane voltage that mediates export of K+. May be involved in sperm capacitation and/or the acrosome reaction, essential steps in fertilization where changes in both intracellular pH and membrane potential are known to occur. In contrast to KCNMA1/SLO1, it is not activated by Ca2+ or Mg2+.
Subcellular location: Membrane; Multi-pass membrane protein
Tissue specificity: Testis-specific. Mainly expressed in spermatocytes.
Detected in brain and brainstem, in vestibular and oculomotor nuclei, the medial nucleus of the trapezoid in the auditory system, in olfactory bulb, red nucleus, and deep cerebellar nuclei. Detected in thalamus, substantia nigra, and amygdala (at protein level). Highly expressed in the brain and kidney.
Highest expression in liver, brain and spinal cord. Lowest expression in skeletal muscle.
Spcs X-react.
Mouse, rat. Other species not yet tested.
Applications info
IHC, WB. A dilution of 1 : 2000 to 1:3000 is recommended. The optimal dilution should be determined by the end user. Not yet tested in other applications.
Storage
Maintain the lyophilised/reconstituted antibodies frozen at -20C for long term storage and refrigerated at 2-8C for a shorter term. When reconstituting, glycerol (1:1) may be added for an additional stability. Avoid freeze and thaw cycles.
Expiry Date
12 months after reconstitution
Shipping
This item will be shipped to you at ambient temperature in a lyophilised form.
References
1. Okazaki N, et al. DNA Res. 10:167-180(2003)
Limitation
For research use only
Immunogen
A synthetic peptide from mouse KCNT1 conjugated to blue carrier protein was used as the antigen.
Conjugate
Unconjugated antibody
Accession
http://www.uniprot.org/uniprot/Q6ZPR4
http://www.uniprot.org/uniprot/Q9Z258
Purity
Whole serum
Clonality
Polyclonal
Specificity
Specific for KCNT1.
Format
Lyophilised
Reconstitution
Reconstitute in 100 ul of sterile water. Centrifuge to remove any insoluble material.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 100ul
Lieferbar: In stock
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