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B3GALT5 Antibody (N-term) Blocking peptide

ArtNr ABC-BP11135a
Hersteller Abcepta
Menge 500 ug
Kategorie
Typ Peptides
Format Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.
Specific against other
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Similar products Beta-1, B3GALT5, 3-galactosyltransferase 5, Beta-3-Gx-T5, UDP-Gal:beta-GlcNAc beta-1, UDP-galactose:beta-N-acetylglucosamine beta-1, 241-, 3-GalTase 5, Beta3Gal-T5, Beta3GalT5, b3Gal-T5
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Primary Accession
Q9Y2C3
Bio Background
This gene is a member of thebeta-1, 3-galactosyltransferase (beta3GalT) gene family. This familyencodes type II membrane-bound glycoproteins with diverse enzymaticfunctions using different donor substrates (UDP-galactose andUDP-N-acetylglucosamine) and different acceptor sugars(N-acetylglucosamine, galactose, N-acetylgalactosamine). Thebeta3GalT genes are distantly related to the Drosophila Brainiacgene and have the protein coding sequence contained in a singleexon. The beta3GalT proteins also contain conserved sequences notfound in the beta4GalT or alpha3GalT proteins. The carbohydratechains synthesized by these enzymes are designated as type 1, whereas beta4GalT enzymes synthesize type 2 carbohydrate chains.The ratio of type 1:type 2 chains changes during embryogenesis. Bysequence similarity, the beta3GalT genes fall into at least twogroups: beta3GalT4 and 4 other beta3GalT genes (beta3GalT1-3, beta3GalT5). This gene encodes the most probable candidate forsynthesis of the type 1 Lewis antigens which are frequently foundto be elevated in gastrointestinal and pancreatic cancers. Theencoded protein is inactive with N-linked glycoproteins andfunctions in mucin glycosylation. Five transcript variants havebeen described which differ in the 5' UTR. All transcript variantsencode an identical protein.
Bio References
Hamshere, M.L., et al. Br J Psychiatry 195(1):23-29(2009)Lin, C.H., et al. Glycobiology 19(4):418-427(2009)Seko, A., et al. Tumour Biol. 30(1):43-50(2009)Mare, L., et al. J. Biol. Chem. 282(1):49-57(2007)Hu, Y.H., et al. BMC Genomics 7, 155 (2006) :
Gene ID
10317
Gene Name
B3GALT5 (HGNC:920)
Subtitle
Synthetic peptide

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Menge: 500 ug
Lieferbar: In stock
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