APP Antibody (Center) Blocking peptide

Peptides; Blocking Peptides

This gene encodes a cell surface receptor andtransmembrane precursor protein that is cleaved by secretases toform a number of peptides. Some of these peptides are secreted andcan bind to the acetyltransferase complex APBB1/TIP60 to promotetranscriptional activation, while others form the protein basis ofthe amyloid plaques found in the brains of patients with Alzheimerdisease. Mutations in this gene have been implicated in autosomaldominant Alzheimer disease and cerebroarterial amyloidosis(cerebral amyloid angiopathy). Multiple transcript variantsencoding several different isoforms have been found for this gene.

Synthetic peptide

Amyloid beta A4 protein, ABPP, APPI, APP, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, CVAP, PreA4, Protease nexin-II, PN-II, N-APP, Soluble APP-alpha, S-APP-alpha, Soluble APP-beta, S-APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, Beta-amyloid protein 40, Beta-APP40, C83, P3(42), P3(40), C80, Gamma-secretase C-terminal fragment 59, Amyloid intracellular domain 59, AICD-59, AID(59), Gamma-CTF(59), Gamma-secretase C-terminal fragment 57, Amyloid intracellular domain 57, AICD-57, AID(57), Gamma-CTF(57), Gamma-secretase C-terminal fragment 50, Amyloid intracellular domain 50, AICD-50, AID(50), Gamma-CTF(50), C31, APP, A4, AD1