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Stanniocalcin-2 (STC2) Antibody (N-term) Blocking peptide

ArtNr ABC-BP1443a
Hersteller Abcepta
Menge 500 ug
Kategorie
Typ Peptides
Format Lyophilized
Specific against other
Citations Ishibashi, K., et al., Biochem. Biophys. Res. Commun. 250(2):252-258 (1998).DiMattia, G.E., et al., Mol. Cell. Endocrinol. 146 (1-2), 137-140 (1998).Chang, A.C., et al., Mol. Cell. Endocrinol. 141 (1-2), 95-99 (1998).
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Stanniocalcin-2,STC-2,Stanniocalcin-related protein,STC-related protein,STCRP,STC2
Similar products STC2, Stanniocalcin-2, Stanniocalcin-related protein, STC-2, STCRP, STC-related protein
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Manufacturer - Category
Peptides; Blocking Peptides
Manufacturer - Targets
The synthetic peptide sequence used to generate the antibody AP1443a was selected from the N-term region of human STC2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background
STC2 is a secreted, homodimeric glycoprotein that is expressed in a wide variety of tissues and may have autocrine or paracrine functions. The encoded protein has 10 of its 15 cysteine residues conserved among stanniocalcin family members and is phosphorylated by casein kinase 2 exclusively on its serine residues. Its C-terminus contains a cluster of histidine residues which may interact with metal ions. The protein may play a role in the regulation of renal and intestinal calcium and phosphate transport, cell metabolism, or cellular calcium/phosphate homeostasis. Constitutive overexpression of human stanniocalcin 2 in mice resulted in pre- and postnatal growth restriction, reduced bone and skeletal muscle growth, and organomegaly. Expression is induced by estrogen and altered in some breast cancers.
Gene Name
STC2
Subtitle
Synthetic peptide
Formulation
Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 500 ug
Lieferbar: In stock
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