NHP2 Antibody (Center) Blocking Peptide

This gene is a member of the H/ACA snoRNPs (smallnucleolar ribonucleoproteins) gene family. snoRNPs are involved invarious aspects of rRNA processing and modification and have beenclassified into two families: C/D and H/ACA. The H/ACA snoRNPs alsoinclude the DKC1, NOLA1 and NOLA3 proteins. These four H/ACA snoRNPproteins localize to the dense fibrillar components of nucleoli andto coiled (Cajal) bodies in the nucleus. Both 18S rRNA productionand rRNA pseudouridylation are impaired if any one of the fourproteins is depleted. The four H/ACA snoRNP proteins are alsocomponents of the telomerase complex. This gene encodes a proteinrelated to Saccharomyces cerevisiae Nhp2p. Alternative splicingresults in multiple transcript variants.

55651

Synthetic peptide