AP3M1 Antibody (C-term) Blocking Peptide

The protein encoded by this gene is the medium subunit ofAP-3, which is an adaptor-related protein complex associated withthe Golgi region as well as more peripheral intracellularstructures. AP-3 facilitates the budding of vesicles from the Golgimembrane and may be directly involved in protein sorting to theendosomal/lysosomal system. AP-3 is a heterotetrameric proteincomplex composed of two large subunits (delta and beta3), a mediumsubunit (mu3), and a small subunit (sigma 3). Mutations in one ofthe large subunits of AP-3 have been associated with theHermansky-Pudlak syndrome, a genetic disorder characterized bydefective lysosome-related organelles. Alternatively splicedtranscript variants encoding the same protein have been observed.

26985

Synthetic peptide