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Mouse Runx1 Blocking Peptide (C-term)

Mouse Runx1 Blocking Peptide (C-term)

ArtNr	ABC-BP21302b
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Molecular Targets for Neuroscience Neural Development By Cell Type Carcinoma Hematology Leukemia Lymphoma Melanoma Sarcoma Peptides & Proteins Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Bae S.-C.,et al.Oncogene 8:809-814(1993). Bae S.-C.,et al.Mol. Cell. Biol. 14:3242-3252(1994). Calabi F.,et al.Submitted (APR-1996) to the EMBL/GenBank/DDBJ databases. Tsuji K.,et al.Biochem. Biophys. Res. Commun. 274:171-176(2000). Fujita Y.,et al.Biochem. Biophys. Res. Commun. 281:1248-1255(2001).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Runt-related transcription factor 1,Acute myeloid leukemia 1 protein,Core-binding factor subunit alpha-2,CBF-alpha-2,Oncogene AML-1,Polyomavirus enhancer-binding protein 2 alpha B subunit,PEA2-alpha B,PEBP2-alpha B,SL3-3 enhancer factor 1 alpha B subunit,SL3/AKV core-binding factor alpha B subunit,Runx1,Aml1,Cbfa2,Pebp2ab
Similar products	Runx1, Acute myeloid leukemia 1 protein, Runt-related transcription factor 1, Core-binding factor subunit alpha-2, CBF-alpha-2, Oncogene AML-1, Polyomavirus enhancer-binding protein 2 alpha B subunit, PEA2-alpha B, PEBP2-alpha B, SL3-3 enhancer factor 1 alpha B subunit, SL3/AKV core-binding factor alpha B subunit, Aml1, Cbfa2, Pebp2ab
Lieferbar
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence is selected from aa 426-439 of HUMAN Runx1
Bio Background	CBF binds to the core site, 5'-PYGPYGGT-3', of a number of enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers, LCK, IL-3 and GM-CSF promoters. Essential for the development of normal hematopoiesis. Isoform 4 shows higher binding activities for target genes and binds TCR-beta-E2 and RAG-1 target site with threefold higher affinity than other isoforms. It is less effective in the context of neutrophil terminal differentiation. Acts synergistically with ELF4 to transactivate the IL-3 promoter and with ELF2 to transactivate the BLK promoter. Inhibits KAT6B- dependent transcriptional activation (By similarity).
Gene Name	Runx1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP21302b-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 13 Tage sparen

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