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P-Glycoprotein (ABCB1) Antibody (Center) Blocking peptide

P-Glycoprotein (ABCB1) Antibody (Center) Blocking peptide

ArtNr	ABC-BP6111a
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology By Cell Type Carcinoma Hematology Leukemia Sarcoma Peptides & Proteins Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Saito, S., et al., J. Hum. Genet. 47(1):38-50 (2002).Kerb, R., et al., Pharmacogenomics 2(1):51-64 (2001).Cascorbi, I., et al., Clin. Pharmacol. Ther. 69(3):169-174 (2001).Hoffmeyer, S., et al., Proc. Natl. Acad. Sci. U.S.A. 97(7):3473-3478 (2000).Mickley, L.A., et al., Blood 91(5):1749-1756 (1998).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Multidrug resistance protein 1,ATP-binding cassette sub-family B member 1,P-glycoprotein 1,CD243,ABCB1,MDR1,PGY1
Similar products	ABCB1, MDR1, PGY1, Multidrug resistance protein 1, ATP-binding cassette sub-family B member 1, P-glycoprotein 1, CD243
Lieferbar
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6111a was selected from the Center region of human ABCB1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	The membrane-associated ABCB1 protein is a member of the superfamily of ATP-binding cassette (ABC) transporters. ABC proteins transport various molecules across extra- and intra-cellular membranes. ABC genes are divided into seven distinct subfamilies (ABC1, MDR/TAP, MRP, ALD, OABP, GCN20, White). This protein is a member of the MDR/TAP subfamily. Members of the MDR/TAP subfamily are involved in multidrug resistance. ABCB1 is an ATP-dependent drug efflux pump for xenobiotic compounds with broad substrate specificity. It is responsible for decreased drug accumulation in multidrug-resistant cells and often mediates the development of resistance to anticancer drugs. This protein also functions as a transporter in the blood-brain barrier.
Gene Name	ABCB1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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ABC-BP6111a-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 13 Tage sparen

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