MMP27 Antibody (C-term) Blocking Peptide

Peptides; Blocking Peptides

Matrix Metalloproteases (MMPs) are zinc-dependent endopeptidases that break down the extracellular matrix, and thus play important roles in many physiological processes including embryonic development, wound healing, reproduction, tissue remodeling, arthritis, cancer and cardiovascular disease. Although most MMPs are secreted, the membrane-type MMPs (MT-MMPs) are anchored to the cell membrane by a transmembrane and intracytoplasmic domain. MMP activities are regulated at several levels, including cleavage of proenzyme forms and suppression via tissue inhibitors of metalloproteinases (TIMPs). The 513 amino acid human MMP27 protein is located primarily in extracellular spaces in the extracellular matrix, and maps to chromosome 11q24.

Synthetic peptide