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APP Antibody (C-term D672) Blocking Peptide

APP Antibody (C-term D672) Blocking Peptide

ArtNr	ABC-BP6306c
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology Neuroscience Molecular Targets for Neuroscience Aging & Neurological Disorders Protein Aggregation, Clearance & Misfolding By Cell Type Peptides & Proteins Adenocarcinoma Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Blomqvist, M.E., et al., Neurobiol. Aging 26(6):795-802 (2005).Yoon, I.S., et al., J. Biol. Chem. 280(20):20140-20147 (2005).Chen, M., et al., Biochem. Biophys. Res. Commun. 330(3):714-721 (2005).Yamamoto, M., et al., Am. J. Pathol. 166(5):1475-1485 (2005).Moir, R.D., et al., J. Biol. Chem. 280(17):17458-17463 (2005).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Amyloid beta A4 protein,ABPP,APPI,APP,Alzheimer disease amyloid protein,Cerebral vascular amyloid peptide,CVAP,PreA4,Protease nexin-II,PN-II,N-APP,Soluble APP-alpha,S-APP-alpha,Soluble APP-beta,S-APP-beta,C99,Beta-amyloid protein 42,Beta-APP42,Beta-amyloid protein 40,Beta-APP40,C83,P3(42),P3(40),C80,Gamma-secretase C-terminal fragment 59,Amyloid intracellular domain 59,AICD-59,AID(59),Gamma-CTF(59),Gamma-secretase C-terminal fragment 57,Amyloid intracellular domain 57,AICD-57,AID(57),Gamma-CTF(57),Gamma-secretase C-terminal fragment 50,Amyloid intracellular domain 50,AICD-50,AID(50),Gamma-CTF(50),C31,APP,A4,AD1
Similar products	APP, A4, AD1, Amyloid beta A4 protein, ABPP, APPI, Alzheimer disease amyloid protein, Cerebral vascular amyloid peptide, PreA4, Protease nexin-II, N-APP, Soluble APP-alpha, Soluble APP-beta, C99, Beta-amyloid protein 42, Beta-APP42, CVAP, Beta-APP40, Beta-amyloid protein 40, PN-II, C31, C80, C83, AICD-50, AICD-57, AICD-59, AID(50), AID(57), AID(59), Amyloid intracellular domain 50, Amyloid intracellular domain 57, Amyloid intracellular domain 59, Gamma-CTF(50), Gamma-CTF(57), Gamma-CTF(59), S-APP-alpha, S-APP-beta, P3(42), P3(40), Gamma-secretase C-terminal fragment 59, Gamma-secretase C-terminal fragment 57, Gamma-secretase C-terminal fragment 50
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Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP6306c was selected from the C-term region of human APP. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	APP is a cell surface receptor and transmembrane precursor protein that is cleaved by secretases to form a number of peptides. Some of these peptides are secreted and can bind to the acetyltransferase complex APBB1/TIP60 to promote transcriptional activation, while others form the protein basis of the amyloid plaques found in the brains of patients with Alzheimer disease. Mutations in this gene have been implicated in autosomal dominant Alzheimer disease and cerebroarterial amyloidosis (cerebral amyloid angiopathy).
Gene Name	APP
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP6306c-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 14 Tage sparen

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