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IDH1 Antibody (N-term) Blocking Peptide

IDH1 Antibody (N-term) Blocking Peptide

ArtNr	ABC-BP7454a
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Sarcoma Peptides & Proteins Myelofibrosis Astrocytoma Peptides By Organ Brain Cancer
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Geisbrecht B.V., Gould S.J.J. Biol. Chem. 274:30527-30533(1999)Xu X., Zhao J., Xu Z.J. Biol. Chem. 279:33946-33957(2004) Bleeker F.E., Lamba S.Hum. Mutat. 30:7-11(2009)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Isocitrate dehydrogenase [NADP] cytoplasmic,IDH,Cytosolic NADP-isocitrate dehydrogenase,IDP,NADP(+)-specific ICDH,Oxalosuccinate decarboxylase,IDH1,PICD
Similar products	IDH1, IDH, IDP, PICD, Cytosolic NADP-isocitrate dehydrogenase, Isocitrate dehydrogenase [NADP] cytoplasmic, Oxalosuccinate decarboxylase, NADP(+)-specific ICDH
Lieferbar
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7454a was selected from the N-term region of human IDH1. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	IDH1 belongs to two distinct subclasses. The protein is the NADP(+)-dependent isocitrate dehydrogenase found in the cytoplasm and peroxisomes. This protein contains the PTS-1 peroxisomal targeting signal sequence. The presence of this enzyme in peroxisomes suggests roles in the regeneration of NADPH for intraperoxisomal reductions, such as the conversion of 2, 4-dienoyl-CoAs to 3-enoyl-CoAs, as well as in peroxisomal reactions that consume 2-oxoglutarate, namely the alpha-hydroxylation of phytanic acid. The cytoplasmic enzyme serves a significant role in cytoplasmic NADPH production.
Gene Name	IDH1
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP7454a-datasheet.pdf

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Einfache Bestellung Periodische Bestellung

Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 14 Tage sparen

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