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PDGFRA Antibody (Y720) Blocking Peptide

PDGFRA Antibody (Y720) Blocking Peptide

ArtNr	ABC-BP7666d
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology Neuroscience Neural Lineage Markers Neuroinflammation By Cell Type Blastoma Carcinoma Glioma Hematology Leukemia Lymphoma Myeloma Melanoma Sarcoma Peptides & Proteins Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Wilczynski, S.P., et al., Hum. Pathol. 36(3):242-249 (2005).Hiwatari, M., et al., Leukemia 19(3):476-477 (2005).Debiec-Rychter, M., et al., Gastroenterology 128(2):270-279 (2005).Sakurai, S., et al., Hum. Pathol. 35(10):1223-1230 (2004).Subramanian, S., et al., Oncogene 23(47):7780-7790 (2004).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Platelet-derived growth factor receptor alpha,PDGF-R-alpha,PDGFR-alpha,Alpha platelet-derived growth factor receptor,Alpha-type platelet-derived growth factor receptor,CD140 antigen-like family member A,CD140a antigen,Platelet-derived growth factor alpha receptor,Platelet-derived growth factor receptor 2,PDGFR-2,CD140a,PDGFRA,PDGFR2,RHEPDGFRA
Similar products	PDGFRA, Platelet-derived growth factor receptor alpha, Alpha platelet-derived growth factor receptor, Alpha-type platelet-derived growth factor receptor, CD140 antigen-like family member A, Platelet-derived growth factor alpha receptor, PDGFR2, RHEPDGFRA, CD140a antigen, PDGF-R-alpha, CD140a, PDGFR-alpha, PDGFR-2, Platelet-derived growth factor receptor 2
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Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7666d was selected from the Y720 region of human PDGFRA. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes.
Gene Name	PDGFRA
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP7666d-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

Express-Lieferung: 14 Tage sparen

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