Runx2 Antibody (N-term) Blocking Peptide

ArtNr	ABC-BP7735a
Hersteller	Abcepta
Menge	500 ug
Kategorie	Neuroscience Neural Development Peptides & Proteins Peptides
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Rich,J.T., Biochem. Biophys. Res. Commun. 372 (1), 230-235 (2008)Ermakov,S., Ann. Hum. Genet. 72 (PT 4), 510-518 (2008)Endo,T., J. Clin. Endocrinol. Metab. 93 (6), 2409-2412 (2008)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Runt-related transcription factor 2,Acute myeloid leukemia 3 protein,Core-binding factor subunit alpha-1,CBF-alpha-1,Oncogene AML-3,Osteoblast-specific transcription factor 2,OSF-2,Polyomavirus enhancer-binding protein 2 alpha A subunit,PEA2-alpha A,PEBP2-alpha A,SL3-3 enhancer factor 1 alpha A subunit,SL3/AKV core-binding factor alpha A subunit,RUNX2,AML3,CBFA1,OSF2,PEBP2A
Similar products	RUNX2, CBFA1, OSF2, AML3, PEBP2A, Runt-related transcription factor 2, Acute myeloid leukemia 3 protein, Core-binding factor subunit alpha-1, Oncogene AML-3, Osteoblast-specific transcription factor 2, CBF-alpha-1, Polyomavirus enhancer-binding protein 2 alpha A subunit, PEBP2-alpha A, PEA2-alpha A, SL3-3 enhancer factor 1 alpha A subunit, SL3/AKV core-binding factor alpha A subunit, OSF-2
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Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP7735a was selected from the N-term region of human Runx2. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	Runx2 is a member of the RUNX family of transcription factors. It is a nuclear protein with an Runt DNA-binding domain. This protein is essential for osteoblastic differentiation and skeletal morphogenesis and acts as a scaffold for nucleic acids and regulatory factors involved in skeletal gene expression. It can bind DNA both as a monomer or, with more affinity, as a subunit of a heterodimeric complex. Mutations in the Runx2 gene have been associated with the bone development disorder cleidocranial dysplasia (CCD).
Gene Name	RUNX2
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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ABC-BP7735a-datasheet.pdf

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Menge: 500 ug

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