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BUB1B Antibody (Center) Blocking Peptide

BUB1B Antibody (Center) Blocking Peptide

ArtNr	ABC-BP8059b
Hersteller	Abcepta
Menge	500 ug
Kategorie	Oncology Peptides & Proteins Peptides By Organ Lung Cancer Skin Cancer Colorectal Cancer Breast Cancer
Typ	Peptides
Format	Lyophilized
Specific against	other
Citations	Cahill, D.P., et al., Genomics 58(2):181-187 (1999).Davenport, J.W., et al., Genomics 55(1):113-117 (1999).Chan, G.K., et al., J. Cell Biol. 143(1):49-63 (1998).Cahill, D.P., et al., Nature 392(6673):300-303 (1998).Taylor, S.S., et al., J. Cell Biol. 142(1):1-11 (1998).
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Mitotic checkpoint serine/threonine-protein kinase BUB1 beta,MAD3/BUB1-related protein kinase,hBUBR1,Mitotic checkpoint kinase MAD3L,Protein SSK1,BUB1B,BUBR1,MAD3L,SSK1
Similar products	BUB1B, BUBR1, MAD3L, SSK1, Mitotic checkpoint serine/threonine-protein kinase BUB1 beta, MAD3/BUB1-related protein kinase, Mitotic checkpoint kinase MAD3L, Protein SSK1, hBUBR1
Lieferbar
Manufacturer - Category	Peptides; Blocking Peptides
Manufacturer - Targets	The synthetic peptide sequence used to generate the antibody AP8059b was selected from the Center region of human BUB1B. A 10 to 100 fold molar excess to antibody is recommended. Precise conditions should be optimized for a particular assay.
Bio Background	BUB1B, a member of the Ser/Thr protein kinase family, is a probable component of the mitotic checkpoint that delays anaphase until all chromosomes are properly attached to the mitotic spindle. It can interact with BUB3, CENP-F, CENP-E and mitosin, and can be localized to nuclear kinetochores. This protein is highly expressed in thymus and spleen. The CD1 domain directs kinetochore localization and binding to BUB3. The protein possesses a cyclin destruction box sequence, which targets protein for rapid degradation by ubiquitin-dependent proteolysis during the transition from mitosis to interphase. Defects in BUB1B are associated with tumor formation.
Gene Name	BUB1B
Subtitle	Synthetic peptide
Formulation	Peptides are lyophilized in a solid powder format. Peptides can be reconstituted in solution using the appropriate buffer as needed.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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ABC-BP8059b-datasheet.pdf

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Menge: 500 ug

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Lieferung vsl. bis 06.11.2025

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