Kif5B-1 Antibody (Central) Blocking Peptide

Peptides; Blocking Peptides

Kinesin is a microtubule-associated force-producing protein that may play a role in organelle transport. It is composed of an oligomer consisting of two heavy chains and two light chains. Kinesin, which is thought to interact with GRIP1, possesses three structural domains: a large globular N-terminal domain which is responsible for the motor activity of kinesin (it hydrolyzes ATP and binds microtubule), a central alpha-helical coiled coil domain that mediates the heavy chain dimerization; and a small globular C-terminal domain which interacts with other proteins (such as the kinesin light chains), vesicles and membranous organelles. Kinesin is found in newborn and adult brain, liver, kidney, spleen, heart, lung and sciatic nerve.

Synthetic peptide