ß-Amyloid (1-42), HiLexa™ Fluor 488-labeled

beta-amyloid, beta-amyloid (1-42)

RT

5030.8

This is a fluorescent (HiLexa™ Fluor 488) labeled ß-Amyloid peptide, Abs/Em=503/528 nm. HiLexa 488™ Fluor labeled Aß (1-42) offers brighter intensity with high fluorescence quantum yield and photostability suitable for pH-insensitive applications including flow cytometry and imaging. HiLexa™ Fluor 488 has the same structure as that of Alexa® Fluor 488.
Aß (1-42), a major component of amyloid plaques and accumulates in neurons of Alzheimer’s disease (AD) brains.
Solvent Information - HiLexa™ Fluor 488 labeled ß-Amyloid peptide can be used in studies applicable for monitoring aggregation kinetics of A? via steady-state fluorescence, measuring amyloid aggregates in cellular compartments in live neurons via confocal microscopy, quantification of A?(1-42) by flow cytometry upon cellular uptake, monitoring A? fibrillogenesis via fluorescence correlation spectroscopy, assaying A? degradation, evaluating role of autophagy in cell lines via immunoblotting, in vitro phagocytosis assay to determine uptake efficacy by macrophages, and a host of other applications including immunocytochemistry, RT-PCR etc.

528

Fluorescent

Research use

5400535177669