DGCR6, Recombinant, Human, aa1-220, His-Tag (DiGeorge Syndrome Critical Region Gene 6)

Blue Ice

27

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M NaCl, 20% glycerol.

DGCR6 shares homology with the Drosophila melanogaster gonadal protein, which participates in gonadal and germ cell development, and with the gamma-1 subunit of human laminin. This protein is a candidate for involvement in DiGeorge syndrome pathology and in schizophrenia.

Source:
Recombinant protein corresponding to human DGCR6, fused to His-tag at N-terminal expressed in E.coli.

Molecular Weight:
~27kD (243aa) (MALDI-TOF)

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMERYAGA LEEVADGARQ QERHYQLLSA LQSLVKELPS SFQQRLSYTT LSDLALALLD GTVFEIVQGL LEIQHLTEKS LYNQRLRLQN EHRVLRQALR QKHQEAQQAC RPHNLPVLQA AQQRELEAVE HRIREEQRAM DQKIVLELDR KVADQQSTLE KAGVAGFYVT TNPQELMLQM NLLELIRKLQ QRGCWAGKAA LGLGGPWQLP AAQCDQKGSP VPP

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.