GAL, Recombinant, Human, aa20-123, His-Tag (Galanin Peptides Preproprotein, GALN, GLNN, GMAP)

Blue Ice

13, 9

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 0.2M NaCl, 50% glycerol, 2mM DTT.

Galanin peptides preproprotein, also known as GAL, is localized in brain pathways involved in both cognition and affect, and may inhibit learning and memory by inhibiting neurotransmitter release and neuronal firing rate. It modulates a variety of physiological processed including cognition/memory, sensory/pain processing, neurotransmitter/hormone secretion, and feeding behavior. GAL is upregulated in primary afferent and sympathetic neurones and may be involved in the development of sympathetic perineuronal baskets (“rings”) following nerve injury.

Source:
Recombinant protein corresponding to human GAL, fused to His-tag at N-terminal expressed in E.coli.

Molecular Weight:
~13.9kD (127aa) (MALDI-TOF)

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSASAGLWS PAKEKRGWTL NSAGYLLGPH AVGNHRSFSD KNGLTSKREL RPEDDMKPGS FDRSIPENNI MRTIIEFLSF LHLKEAGALD RLLDLPAAAS SEDIERS

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.