RHOQ, Recombinant, Human, aa1-202, His-Tag (Rho-related GTP-binding Protein RhoQ Precursor, ARHQ, RASL7A, TC10, TC10A)

Blue Ice

24, 7

Supplied as a liquid in 20mM Tris-HCl buffer, pH 8.0, 10% glycerol, 1mM DTT.

RHOQ, also known as rho-related GTP-binding protein RhoQ, is a small signaling G protein (more specifically a GTPase), and is a member of the Rac subfamily of the family Rho family of GTPases. It involved in epithelial cell polarization processes. It may play a role in CFTR trafficking to the plasma membrane. It causes the formation of thin, actin-rich surface projections called filopodia.

Source:
Recombinant protein corresponding to human RhoQ, fused to His-tag at N-terminal expressed in E.coli.

Molecular Weight:
~24.7kD (225aa) (MALDI-TOF)

AA Sequence:
MGSSHHHHHH SSGLVPRGSH MGSMAHGPGA LMLKCVVVGD GAVGKTCLLM SYANDAFPEE YVPTVFDHYA VSVTVGGKQY LLGLYDTAGQ EDYDRLRPLS YPMTDVFLIC FSVVNPASFQ NVKEEWVPEL KEYAPNVPFL LIGTQIDLRD DPKTLARLND MKEKPICVEQ GQKLAKEIGA CCYVECSALT QKGLKTVFDE AIIAILTPKK HTVKKRIGSR CINCC

Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing.. Store at -20°C. Aliquots are stable for 6 months after receipt at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.