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HEK293/Human APP (GFP) Stable Cell Line

HEK293/Human APP (GFP) Stable Cell Line

ArtNr	CHEK-ATP081-2Vials
Hersteller	ACROBiosystems
Menge	2 vials
Kategorie	Peptides & Proteins Recombinant Proteins
Typ	Proteins Recombinant
Format	Liquid
Specific against	Human (Homo sapiens)
Host	HEK293
Konjugat/Tag	GFP
Dry ice	Yes
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Trockeneis
Lieferbar
Manufacturer - Applications	• Screening β-secretase and γ-secretase inhibitors which stops Aβ peptide formation.
Manufacturer - Category	Cell
Manufacturer - Conjugate / Tag	GFP Tag
Shipping Temperature	Dry ice
Storage Conditions	Frozen in liquid nitrogen
Manufacturer - Format	Liquid
Description	Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain, releasing sAPPβ from a membrane-anchored fragment named βCTF or C103, which is subsequently cleaved by γ-secretase to release Aβ.
Background	Amyloid precursor protein (APP) is a type I integral membrane protein ubiquitously expressed in many tissues and concentrated in the synapses of neurons. The majority of APP is cleaved at the plasma membrane by the α-secretase in the non-amyloidogenic pathway. The amyloidogenic pathway starts with β-secretase cleavage by BACE1 on the N-terminal part of the Aβ domain, releasing sAPPβ from a membrane-anchored fragment named βCTF or C103, which is subsequently cleaved by γ-secretase to release Aβ.
Molecule	APP

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Arbeitsanleitung (Data Sheet) anfordern

CHEK-ATP081-2Vials-datasheet.pdf

CHEK-ATP081-2Vials-safety-datasheet.pdf