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Recombinant Human Microfibrillar-associated Protein 2

Recombinant Human Microfibrillar-associated Protein 2

ArtNr	pro-1265-10ug
Hersteller	ProSpec
Menge	10ug
Kategorie	Neuroscience Neural Lineage Markers Peptides & Proteins Recombinant Proteins Neurodegeneration Markers
Typ	Proteins
Specific against	Human (Homo sapiens)
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Lieferbar
Synonyms	Microfibrillar-associated protein 2, MFAP-2, Microfibril-associated glycoprotein 1, MAGP, MAGP-1, MFAP2, MAGP1
Introduction	Microfibrillar-associated protein 2 (MFAP2) is an O-glycosylated protein discharged to the extracellular space and the extracellular matrix. MFAP2 connects with biglycan and elastin in a ternary complex. MFAP2 plays a key role in the support and distensibility of the juxtacanalicular region of these collector channels. MFAP2 inhibits LTB-1 binding to fibrillin-1, promotes the phosphorylation of Smad2 thus mediating the consequent extracellular deposition of latent TGFbeta.
Description	MFAP2 Human Recombinant produced in E.Coli is a single, non-glycosylated polypeptide chain containing 190 amino acids (18-183 a.a) and having a molecular mass of 21.5kDa. MFAP2 is fused to a 24 amino acid His-tag at N-terminus purified by proprietary chromatographic techniques.
Source	Escherichia Coli.
Physical Appearance	Sterile Filtered clear solution.
Formulation	MFAP2 protein solution (0.5mg/ml) containing 20mM Tris-HCl buffer (pH 8.0), 1M Urea and 20% glycerol.
Purity	Greater than 90.0% as determined by SDS-PAGE.
Usage	ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals.
Amino acid sequence	MGSSHHHHHH SSGLVPRGSH MGSM QGQYDL DPLPPFPDHV QYTHYSDQID NPDYYDYQEV TPRPSEEQFQ FQSQQQVQQE VIPAPTPEPG NAELEPTEPG PLDCREEQYP CTRLYSIHRP CKQCLNEVCF YSLRRVYVIN KEICVRTVCA HEELLRADLC RDKFSKCGVM ASSGLCQSVA ASCARSCGSC.
Storage	Store at 4C if entire vial will be used within 2-4 weeks. Store, frozen at -20C for longer periods of time. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Avoid multiple freeze-thaw cycles.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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pro-1265-10ug-safety-datasheet.pdf