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Human CD33/Siglec-3 protein, His tag (Animal-Free)

Human CD33/Siglec-3 protein, His tag (Animal-Free)

ArtNr	ABK-PRP2032-10ug
Hersteller	Abbkine Scientific
Menge	10ug
Kategorie	Oncology Neuroscience Neuroinflammation By Cell Type Hematology Leukemia Myeloma Peptides & Proteins Recombinant Proteins
Typ	Proteins
Specific against	other
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
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Sequence	Amino acid sequence derived from human CD33 protein (AAA51948, Met1-His259) was expressed with a polyhistidine tag at the C-terminus.
Protein length	The recombinant human CD33/Siglec-3 protein consists of 248 amino acids and predicts a molecular mass of 27.3 kD.The apparent molecular mass of the human CD33 is approximately 40-55 kDa in SDS-PAGE under reducing conditions due to glycosylation.
Preparation method	HEK 293 Cells
Purity	>95% as determined by SDS-PAGE
Formulation	0.22 um filtered protein solution is in PBS, pH 7.4.
Features & Benefits	Endotoxin: <0.1 EU per ug of the protein as determined by the LAL method.
Molecular weight	27.3 kDa
Usage notes	Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD33/Siglec-3 protein using the buffer we provided not less than 100 ug/mL, which can then be further diluted to other aqueous solutions.
Storage instructions	Lyophilized humanCD33/Siglec-3 protein product should be stored desiccated below -20C. Upon reconstitution, the protein should be stored at 4C between 2-7 days and for future use below -20C. For long term storage it is recommended to add a carrier protein (0.1% HSA or BSA). Please prevent freeze-thaw cycles.
Shipping	The product is shipped at ambient temperature.
Precautions	The product listed herein is for research use only and is not intended for use in human or clinical diagnosis. Suggested applications of our products are not recommendations to use our products in violation of any patent or as a license. We cannot be responsible for patent infringements or other violations that may occur with the use of this product.
Background	The transmembrane protein CD33 is a sialic acid-binding immunoglobulin-like lectin that mediate the cell-cell interaction and inhibiting normal functions of immune cells. CD33 (siglec-3), a well-known target in leukemia therapy, is an inhibitory sialoadhesin expressed in human leukocytes of the myeloid lineage and some lymphoid subsets, including NK cells. It may constitute a control mechanism of the innate immune system. In the brain, CD33 is mainly expressed on microglial cells.
Gene ID	945
Alternative	CD33 Molecule; SIGLEC3; Sialic Acid-Binding Ig-Like Lectin 3; Myeloid Cell Surface Antigen CD33; CD33 Antigen (Gp67); SIGLEC-3; Gp67; Sialic Acid Binding Ig-Like Lectin 3; CD33 Molecule Transcript 3; CD33 Antigen
Accession	P20138
Tag	CD33/Siglec-3
Description	Recombinant Human CD33/Siglec-3 protein expressed in HEK293 Cells.

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Menge: 10ug

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Lieferung vsl. bis 04.09.2025

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