Human CD7/GP40 protein, His tag (Animal-Free)

The recombinant human CD7/GP40 protein consists of 161 amino acids and predicts a molecular mass of 18 kD.The apparent molecular mass of the human CD7 is approximately 25-35 kDa in SDS-PAGE under reducing conditions due to glycosylation.

>95% as determined by SDS-PAGE

Endotoxin: <0.1 EU per ug of the protein as determined by the LAL method.

Always centrifuge tubes before opening. It is recommended to reconstitute the lyophilized human CD7/GP40 protein using the buffer we provided not less than 100 ug/mL, which can then be further diluted to other aqueous solutions.

The product is shipped at ambient temperature.

The CD7 antigen is a member of the immunoglobulin superfamily that expresses on the surface of all thymocytes, a majority of mature T cells, and also natural killer cells. Interestingly, under physiological and different pathological conditions, the loss of CD7 antigen occurred in the subset of CD4+ memory T cells. The functions of the cell membrane CD7 antigen have been investigated in human mature T and NK cells, showing the direct involvement of this molecule in multiple effector functions related with activation, proliferation, production of cytokines and modification of adhesion properties. The CD7 glycoprotein is not only expressed by mature lymphoid cells, but also by early hematopoietic progenitors and several types of leukemias, suggesting a role of CD7 during hematopoiesis.

CD7 Molecule; T-Cell Leukemia Antigen; T-Cell Antigen CD7; TP41; T-Cell Surface Antigen Leu-9; CD7 Antigen (P41); P41 Protein; LEU-9; Tp40; CD7 Antigen 4; CD7

CD7/GP40