Recombinant Human HSD17B10 Protein, His Tag

HSD17B10

Q99714

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

HSD17B1 gene encodes the protein 17-beta-hydroxysteroid dehydrogenase 1 that is a member of the short-chain dehydrogenase/reductase superfamily SCHAD. HSD17B1 gene product is a mitochondrial protein that is involved in lipid metabolism, fatty acid oxidation and steroid hormone metabolism. HSD17B1 protein has been implicated in the development of Alzheimer"s disease and mutations in the gene are the cause of 2-methyl-3-hydroxybutyryl-CoA dehydrogenase deficiency (MHBD). Furthermore, HSD17B1 may act as a direct molecular link between beta-amyloid and mitochondrial toxicity.

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