Recombinant Human NovoNectin Protein, No Tag

FN1

P02751

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Protein A/G

Fibronectin (FN) is a large glycoprotein present as soluble disulfide-linked dimeric form in plasma and body fluids, and as dimeric or multimeric form at the cell surface or in extracellular matrix (ECM). Each monomer of FN consists of three types of homologous repeating units, that is 12 type I repeats, two type II repeats and 15-17 type III repeats. The occurrence of multiple isoforms results from alternative mRNA splicing of the ED-A, ED-B and III-CS regions, and subsequent post-translational modification. As an ECM component and one of the primary cell adhesion molecules, Fibronectin can be a ligand for fibrin, heparin, chondroitin sulfate, collagen/gelatin, as well as many integrin receptors through which FN mediates the variety of cellular signaling pathways.

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