Recombinant Human PRSS1/Trypsin-1 Protein, His & Fc Tag

PRSS1

P07477

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

Human Trypsin 1, encoded by the PRSS1 gene, is also known as cationic trypsinogen. Constituting approximately twothirds of the total trypsin content in normal pancreatic juice, it is the most abundant trypsin isoform produced by the pancreas. It contains a signal peptide (residues 115), a pro region (residues 1623), and a mature chain (residues 24247). Trypsin 1 is synthesized in the pancreas and secreted into the duodenum lumen, where it is activated by enterokinase. Its major physiologic function is to digest food and to activate other proenzymes. Mutations in the PRSS1 gene can cause hereditary pancreatitis.

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