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Recombinant Human STAT6 Protein, His Tag

ArtNr KMD-KMH1757-50ug
Hersteller KMD Bioscience
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Specific against Human (Homo sapiens)
Host E.coli
Konjugat/Tag His
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias STAT6B, STAT6C, D12S1644, IL-4-STAT, signal transducer and activator of transcription 6
Lieferbar
Molecular Name
STAT6
Source
This protein contains the human STAT6(Ser627-Ser837) was fused with the C-terminal His Tag and expressed in E. coli.
Uniprot Accession
P42226
Purity
>=90% as determined by SDS-PAGE
Endotoxin
Please contact our customer service for more information.
Buffer
PBS
Purification
Protein A/G
Predicted Molecular Weight
23.21kDa
Background
The STAT6 protein is a member of the STAT family of transcription factors that are activated by cytokines and phosphorylated by the receptor associated kinases. STATs form homo- or hetero-dimers that translocate to the cell nucleus where they act as transcription activators. STAT6 plays a central role in exerting IL4 mediated biological responses. STAT6 induces the expression of BCL2L1/BCL-XL, which is responsible for the anti-apoptotic activity of IL4. STAT6 mRNA has been detected in various tissues including peripheral blood lymphocytes, colon, intestine, ovary, prostate, thymus, spleen, kidney, liver, lung and placenta. STAT6 is critically involved in Th2 immune response.
Storage
Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition
This product is shipped on ice packs or dry ice.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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