Recombinant Human CD158K/KIR3DL2 Protein, His Tag

KIR3DL2

P43630

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

KIR3DL2is a type I transmembrane protein of the p7 family of killer cell Ig-likereceptors (KIR). KIR are expressed on CD56 dim NK cells and T cell subsetswhere they participate in identifying normal and abnormal cells andregulating effector functions of the innate immune system. KIR are named forthe number of Ig-like domains (2D or 3D) in the extracellular domain (ECD)and whether they have long or short (L, S) cytoplasmic tail. As with other inhibitoryKIR, KIR3DL2 has two ITIM domains within its long tail (3). KIR3DL2 isdiverse, with twelve alleles identified and as many as five single amino acid(aa) polymorphisms found in a single individual.

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