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Recombinant Human BMP9/GDF2/GDF2 Protein, His Tag

ArtNr KMD-KMH750-50ug
Hersteller KMD Bioscience
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Specific against Human (Homo sapiens)
Host Mammalian cell
Konjugat/Tag His
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BMP9, HHT5, BMP-9, growth differentiation factor 2
Lieferbar
Molecular Name
GDF2
Source
This protein contains the human GDF2(Ser320-Arg429) was fused with the C-terminal His Tag and expressed in Mammalian cells.
Uniprot Accession
Q9UK05
Purity
>=90% as determined by SDS-PAGE
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer
PBS
Purification
Protein A/G
Predicted Molecular Weight
12.1kDa
Background
Growth differentiation factor 2 (GDF2) is a protein also known as bone morphogenetic protein (BMP)-9 that belongs to the transforming growth factor beta superfamily. It has a role in inducing and maintaining the ability of embryonic basal forebrain cholinergic neurons (BFCN) to respond to a neurotransmitter called acetylcholine; BFCN are important for the processes of learning, memory and attention. GDF2 is also important for the maturation of BFCN. Another role of GDF2 has been recently suggested. GDF2 is a potent inducer of hepcidin (a cationic peptide that has a antimicrobial properties) in liver cells (hepatocytes) and can regulate iron metabolism.
Storage
Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition
This product is shipped on ice packs or dry ice.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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