Recombinant Mouse Activin Rib/Alk-4/Acvr1b Protein, Fc Tag

Acvr1b

Q61271

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

Activin RIB, also known as ALK4, is a glycosylated type I receptor in the superfamily of TGF-beta serine/threonine kinase receptors. Activin RIB associates with Activin RIIB to form a receptor complex for activin and inhibin molecules. These ligands bind to Activin RIIB which then associates with and phosphorylates the cytoplasmic domain of Activin RIB to initiate signal transduction.Within the ECD, human Activin RIB shares 93% and 95% aa sequence identity with mouse and rat Activin RIB, respectively. It shares 25% - 35% aa sequence identity with other human type I receptors Activin RIA, Activin RIC, BMPR-IA, BMPR-IB, and TGF-beta R1.

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