Recombinant Mouse Ephrin-B1/Efnb1 Protein, His Tag

Efnb1

P52795

< 1.0 EU per ug of the protein as determined by the LAL method.

Protein A/G

Ephrin-B1 (EFNB1) is a glycoprotein that is expressed on neuroepithelial cells and post-synaptically on dendritic spines in the cortex, supporting a role in synaptic plasticity in this region. Ephrin-B1 is also highly expressed on developing peripheral nerve fibers including auditory and vestibular (statoacoustic) and dorsal root ganglion nerve fibers and provides guidance signals to these cells. Ephrin-B1 participates in cell-cell repulsive and attractive signaling together with its Eph receptor. Tyrosine phosphorylation of ephrin-B1 promotes invasion of cancer cells in vivo and is a potential therapeutic target in some types of gastrointestinal cancers.

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