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Recombinant Mouse Il12rb2 Protein, Fc Tag

ArtNr KMD-MOP2197-50ug
Hersteller KMD Bioscience
Menge 50 ug
Kategorie
Typ Proteins Recombinant
Specific against Mouse (Murine, Mus musculus)
Host Mammalian cell
Konjugat/Tag Fc
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Ifnm, IL-12RB2, A930027I18Rik, interleukin 12 receptor, beta 2
Lieferbar
Molecular Name
Il12rb2
Source
This protein contains the mouse Il12rb2(Met1-Asn637) was fused with the C-terminal Fc Tag and expressed in Mammalian cells.
Uniprot Accession
P97378
Purity
>=90% as determined by SDS-PAGE
Endotoxin
< 1.0 EU per ug of the protein as determined by the LAL method.
Buffer
PBS
Purification
Protein A/G
Predicted Molecular Weight
95.07kDa
Background
The protein encoded by this gene is a type I transmembrane protein identified as a subunit of the interleukin 12 receptor complex. The coexpression of this and IL12RB1 proteins was shown to lead to the formation of high-affinity IL12 binding sites and reconstitution of IL12 dependent signaling. The expression of this gene is up-regulated by interferon gamma in Th1 cells, and plays a role in Th1 cell differentiation. The up-regulation of this gene is found to be associated with a number of infectious diseases, such as Crohns disease and leprosy, which is thought to contribute to the inflammatory response and host defense.
Storage
Store the product under sterile conditions after opening at -20C to -80C for 12 months. Avoid repeated freeze-thaw cycles.
Shipping Condition
This product is shipped on ice packs or dry ice.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
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