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TL1-A (NT) Blocking Peptide - 50 µg

TL1-A (NT) Blocking Peptide - 50 µg

ArtNr	LEIN-T328-50ug
Hersteller	Leinco Technologies
Menge	50 ug
Kategorie	Oncology Neuroscience Neuroinflammation Metabolism Diabetes By Cell Type Peptides & Proteins Cell Biology Obesity Cell Culture Cytokines Cell Status Necrosis Apoptosis Peptides
Typ	Peptides
Specific against	Human (Homo sapiens)
Citations	1. Wei P et al. (2003) J Biol Chem. 278: 39251 2. Fabio Cominelli et al. (2006) PNAS 103: 8441
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Category	Control Peptides
Manufacturer - Targets	TNF-Ligand-Related Molecule 1-A
Country of Origin	USA
Shipping Temperature	Next Day Ambient
Storage Conditions	Store this peptide in working aliquots at -20°C in a manual defrost freezer. Avoid Repeated Freeze Thaw Cycles.
Product Description	TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.1 TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.2
Background	TNF-ligand-related molecule 1A (TL1A), is an endothelium-derived T cell costimulator and a ligand for tumor necrosis factor receptor superfamily members DR3 and decoy receptor 3.¹ TL1A binds to the death-domain receptor (DR)3 and provides costimulatory signals to activated lymphocytes. Through this interaction, TL1A induces secretion of IFN-γ. Blockade of the TL1A/DR3 pathway may offer therapeutic opportunities in Crohn's disease.²
PubMed	TNF-Ligand-Related Molecule 1-A
Amino acid location	14 amino acids near the amino terminus of human TL1A.
Concentration	0.2 mg/ml
Formulation	This peptide is formulated in PBS pH 7.2 (0.01 M Sodium Phosphate, 0.13 M NaCl) containing 0.1% bovine serum albumin and 0.02% sodium azide.
Additional Information	Each investigator should determine their own optimal working dilution for specific applications. See directions on lot specific datasheets, as information may periodically change.
Keywords	Blocking Peptide, TNF-Ligand-Related Molecule 1-A, TNFSF15, MGC129934, MGC129935, TL1, VEGI, VEGI192A, TL1-A, Human, TL1-A (NT) Blocking Peptide

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 50 ug

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Lieferung vsl. bis 16.10.2025

Express-Lieferung: 3 Tage sparen

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