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PLGF / PGF (19-149) Recombinant Protein

ArtNr PRS-11-161-0.02mg
Hersteller ProSci
Menge 0.02 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB, ELISA
Specific against other
Konjugat/Tag HIS
Purity >90% as determined by SDS-PAGE.
Sequence Leu 19 - Arg 149
Citations Maglione D., et al., 1993, Oncogene 8 (4): 925–31.
Khalil A., et al., 2008, PLoS ONE 3 (7): e2766.
Khurana R., et al., 2005, Circulation 111 (21): 2828–2836.
Rolny C., et al., 2011, Cancer Cell 19:31-44.
NCBI PGF
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias PGF,PLGF,PlGF,PGFL,SHGC-10760
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
16.6 kDa
Background
Placental growth factor (PGF) is also known as vascular endothelial growth factor-related protein, PLGF and PlGF2, is a member of the VEGF (vascular endothelial growth factor) sub-family - a key molecule in angiogenesis and vasculogenesis, in particular during embryogenesis. The main source of PGF during pregnancy is the placental trophoblast. PGF is also expressed in many other tissues, including the villous trophoblast. PGF is actived in angiogenesis and endothelial cell growth, stimulating their proliferation and migration. PlGF2 binds NRP1/neuropilin-1 and NRP2/neuropilin-2 in a heparin-dependent manner. Also promotes cell tumor growth.
By Type
Cancer, Growth Factors, Obesity, Signal Transduction
Buffer
PBS, pH7.4
Application Note
This protein carries a polyhistidine tag at the C-terminus. The protein has a calculated MW of 16.6 kDa. As a result of glycosylation, the protein migrates as 20-30 kDa under reducing (R) condition, and 45-55 kDa under non-reducing (NR) condition (SDS-PAG
NCBI Official Name
placentalgrowthfactor
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
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