Vergleich

TROP-2 / TACSTD2 Recombinant Protein

ArtNr PRS-11-231-0.2mg
Hersteller ProSci
Menge 0.2 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag Fc
Purity >95% as determined by SDS-PAGE.
Sequence His 27 - Thr 274
Citations Simms A., et al., 2016, Diagn. Cytopathol. 44:26-31.
Fornaro M., et al., 1995, Int. J. Cancer. 62(5):610-618.
NCBI TACSTD2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias TACSTD2,GA733-1,M1S1,TROP2
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
54.3 kDa
Background
TROP-2 is a single-copy gene in human cells, and encodes a type-1 transmembrane glycoprotein which is over-expressed in various malignancies, also referred to as tumor associated calcium signal transducer 2 (TACSTD2), GA733-1 or M1S1. TROP-2 is related to epithelial cell adhesion molecule (EpCAM), also called TROP-1, gp40, and KSA. Trop-1 and Trop-2 are homologous to serum IGF-II-binding proteins and appear as signal transducers. Thus, they likely represent novel cell-surface receptors and may play a role in regulating the growth of carcinoma cells.
By Type
Apoptosis, Cancer, Homeostasis, Immunology, Other
Buffer
Tris with Glycine,  Arginine and NaCl,  pH7.5
Application Note
This protein carries a human IgG1 Fc tag at the C-terminus. The protein has a calculated MW of 54.3 kDa. The protein migrates as 60-70 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
NCBI Official Name
tumorassociatedcalciumsignaltransducer2
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.2 mg
Lieferbar: In stock
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