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CD24 Recombinant Protein

ArtNr PRS-11-271-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB, ELISA
Specific against other
Konjugat/Tag IgG Fc
Purity >90% as determined by SDS-PAGE.
Sequence Ser 27 - Gly 59
Citations Suzuki T1, et al. 2001. J Immunol. 166(9):5567-77.
Chen Z, et al. 2017. Biomed Pharmacother. 90:427-436.
Eyvazi S, et al. 2018. Curr Cancer Drug Targets. 18(4):328-336.
NCBI CD24
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias CD24,CD24A
Lieferbar
Manufacturer - Applications
This protein carries a mouse IgG2a Fc tag at the C-terminus. The protein has a calculated MW of 30.0 kDa. The protein migrates as 40-55 kDa under reducing (R) condition (SDS-PAGE) due to glycosylation.
Storage Conditions
Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight
30.0 kDa
Background
CD24 may have a pivotal role in cell differentiation of different cell types. Signaling could be triggered by the binding of a lectin-like ligand to the CD24 carbohydrates, and transduced by the release of second messengers derived from the GPI-anchor. Modulates B-cell activation responses. Promotes AG-dependent proliferation of B-cells, and prevents their terminal differentiation into antibody-forming cells. In association with SIGLEC10 may be involved in the selective suppression of the immune response to danger-associated molecular patterns (DAMPs) such as HMGB1, HSP70 and HSP90. Plays a role in the control of autoimmunity.
Buffer
50 mM Tris, 100 mM Glycine, 150 mM NaCl, pH7.5
NCBI Official Name
CD24molecule
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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