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IGF-Binding Protein 7 Recombinant Protein (Animal Free)

IGF-Binding Protein 7 Recombinant Protein (Animal Free)

ArtNr	PRS-40-765-5ug
Hersteller	ProSci
Menge	5 ug
Kategorie	Oncology Metabolism Diabetes Glucose Homeostasis Cholesterol & Lipid Metabolism Regulation of Appetite By Cell Type Sarcoma Peptides & Proteins Recombinant Proteins Cell Biology Cell Culture Cytokines Cell Status Endocrine Regulation of Lipid Metabolism Senescence
Typ	Proteins Recombinant
Format	Lyophilized
Specific against	other
Purity	≥ 98% by SDS-PAGE gel and HPLC analyses.
Sequence	SSSDTCGPCE PASCPPLPPL GCLLGETRDA CGCCPMCARG EGEPCGGGGA GRGYCAPGME CVKSRKRRKG KAGAAAGGPG VSGVCVCKSR YPVCGSDGTT YPSGCQLRAA SQRAESRGEK AITQVSKGTC EQGPSIVTPP KDIWNVTGAQ VYLSCEVIGI PTPVLIWNKV KRGHYGVQRT ELLPGDRDNL AIQTRGGPEK HEVTGWVLVS PLSKEDAGEY ECHASNSQGQ AS
NCBI	IGFBP7
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	Insulin-like Growth Factor-Binding Protein 7,IBP-7,Mac25,IGF binding protein related protein-1 (IGFBP-rP1)
Versandbedingung	Raumtemperatur
Lieferbar
Manufacturer - Type	Recombinant Proteins
Shipping Temperature	Room Temp
Storage Conditions	The recombinant protein is stable for at least 2 years from date of receipt at -20˚ C. Reconstituted protein is stable for at least 3 months when stored in working aliquots with a carrier protein at -20˚ C. As with any protein, exposing the recombinant protein to repeated freeze / thaw cycles is not recommended. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.
Background	IGF-BPs control the distribution, function and activity of IGFs in various cell tissues and body fluids. Currently, there are seven named IGF-BPs that form high affinity complexes with both IGF-I and IGF-II. IGF-BP7 is expressed in a wide range of normal human tissues, and it generally shows reduced expression in cancer cell lines of prostate, breast, colon, and lung origin. It plays a role in skeletal myogenesis by binding to IGF in a manner that inhibits IGF-induced differentiation of skeletal myoblasts, without affecting IGF-induced proliferation. Additionally, IGF-BP7 suppresses growth and colony formation of prostate and breast cancer cell lines through an IGF-independent mechanism, which causes a delay in the G1 phase of the cell cycle and increased apoptosis. Recombinant Human IGF-BP7 is a 26.4 kDa protein consisting of 256 amino acid residues.
By Type	Apoptosis, Cancer, Obesity
NCBI Official Name	insulin-like growth factor binding protein 7
NCBI Organism	Homo sapiens
Disclaimer	This product is for research use only.
Manufacturer - Species	Human
By Species	Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 5 ug

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Lieferung vsl. bis 04.12.2025