Vergleich

FasL Soluble Recombinant Protein

ArtNr PRS-90-312-10ug
Hersteller ProSci
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Konjugat/Tag Fc
Purity >95% (SDS-PAGE).<br><br> Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Sequence Human FasL (aa 139-281) is fused at the N-terminus to the Fc portion of human IgG1.
NCBI FASLG
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias APO-1L,CD95L,CD178,TNFSF6,Fas Ligand
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Biological Activity
Induces apoptosis of human Jurkat T cells at a concentration of <0.2ng/ml.
Background
Fc (human):FasL, Soluble (human) is a high activity construct in which two trimeric FasL are artificially linked via the Fc binding domain of human IgG1. This construct very effectively simulates the natural membrane-assisted aggregation of FasL in vivo. FasL is a cytokine that binds to TNFRSF6/Fas, a receptor that transduces the apoptotic signal into cells. It is involved in cytotoxic T cell mediated apoptosis and in T cell development.
By Type
Apoptosis, Cancer, Other
Protein Gi #
4557329
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 100 μ l sterile water.
Application Note
This recombinant proteins is for research use only.
NCBI Official Name
Fas ligand (TNF superfamily, member 6)
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human, Mouse
By Species
Human, Mouse

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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