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Irisin Recombinant Protein

ArtNr PRS-90-316-10ug
Hersteller ProSci
Menge 10 ug
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Konjugat/Tag DDDDK
Purity >95% (SDS-PAGE).<br><br> Endotoxin level is less than 0.01EU/ μg purified protein (LAL test; Lonza).
Sequence Irisin (human, aa 32-143 /mouse, aa 29-140) is DDDDK-tagged at the N-terminus. Irisin has 100% identity between mouse, rat, monkey and human.
NCBI FNDC5
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Fibronectin Type III Domain-containing Protein 5 (cleaved),Fibronectin Type III Repeat-containing Protein 2 (cleaved),FNDC5 (cleaved)
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Stable for at least 6 months after receipt when stored at -20˚ C.
Biological Activity
Activates brown adipocyte markers Ucp1 and Cidec in murine subcutaneous adipocytes at 10ng/ml [Lit. 1].
Background
Irisin is a recently described exercise-induced hormone secreted by skeletal muscle in mice and humans. Irisin activates beige fat cells (beige cells have a gene expression pattern distinct from either white or brown fat and are preferentially sensitive to the polypeptide hormone Irisin). Irisin is cleaved from the type I membrane protein FNDC5 and improves systemic metabolism by increasing energy expenditure.
By Type
Obesity
Protein Gi #
403314395
Concentration
0.1mg/ml after reconstitution.
Buffer
Contains PBS. Reconstitute with 100 μ l sterile water.
Application Note
This recombinant proteins is for research use only.
NCBI Official Name
fibronectin type III domain containing 5
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human, Mouse
By Species
Human, Mouse

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 10 ug
Lieferbar: In stock
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