Vergleich

GM-CSF Recombinant Protein

Hersteller ProSci
Kategorie
Typ Proteins Recombinant
Specific against other
Format Lyophilized
Menge 50 ug
ArtNr PRS-90-553-50ug
eClass 6.1 34160400
eClass 9.0 42020190
Lieferbar
Applications
This recombinant proteins is for research use only.
Applications
This recombinant proteins is for research use only.
Buffer
Lyophilized from 0.2μm-filtered solution in 50mM Tris-HCl, 200mM NaCl, pH8.0.
Storage Conditions
Stable for at least 1 year after receipt when stored at -20˚ C. Working aliquots are stable for up to 3 months when stored at -20˚ C.
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Predicted Molecular Weight
~16kDa (SDS-PAGE)
Purity
≥95% (SDS-PAGE).

Endotoxin level is less than <0.1EU/ug protein (LAL test; Lonza).
Background
Human GM-CSF is a 24 kDa glycoprotein produced by a variety of cell types, including T and B lymphocytes, macrophages, keratinocytes, eosinophils, neutrophils, and endothelial cells in response to cytokine or inflammatory stimuli. GM-CSF was initially identified on the basis of its capacity to stimulate the clonal proliferation of myeloid precursors in vitro. GM-CSF promotes a Th1 biased immune response, allergic inflammation, and the development of autoimmunity. GM-CSF are particularly effective as antitumor vaccines. GM-CSF regulates multiple biological activities through activation of the GM-CSF receptor (GMCSFR), a member of the type I cytokine receptor group comprising alpha and beta subunits.
Concentration
0.5mg/ml
Accession #
AAI14000.1
Ncbi Gene Id #
1437
Ncbi Official Symbol
CSF2
Ncbi Official Full Name
colony stimulating factor 2
Ncbi Organism
Homo sapiens
Fusion Tag
C-His-tag
Sequence
Human GM-CSF (aa 18-144) is fused at the C-terminus to a His-tag.
Biological Activity
Measured in a cell proliferation assay using TF-1 human erythroleukemic cells. The ED50 for this effect is typically 0.1-0.6 ng/mL

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 50 ug
Lieferbar: In stock
lieferbar

Lieferung vsl. bis 02.05.2024 

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