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Sclerostin Recombinant Protein

ArtNr PRS-91-919-0.05mg
Hersteller ProSci
Menge 0.05 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Specific against other
Konjugat/Tag HIS
Purity Greater than 95% as determined by reducing SDS-PAGE.<br />Endotoxin level less than 0.1 ng/ug (1 IEU/ug) as determined by LAL test.
Sequence Gln24-Tyr213
NCBI SOST
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias Sclerostin,SOST,UNQ2976,PRO7455,PRO7476
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Manufacturer - Conjugate / Tag
C-6 His tag
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized protein should be stored at -20˚ C, though stable at room temperature for 3 weeks.
Reconstituted protein solution can be stored at 4-7˚ C for 2-7 days.
Aliquots of reconstituted samples are stable at -20˚ C for 3 months.
Molecular Weight
22.3 kD
Background
Sclerostin, also known as SOST, is a member of the Cerberus/DAN family of BMP antagonists. SOST is asecreted glycoprotein with a C-terminal cysteine knot-like (CTCK) domain. It shows sequence similarity to the DAN (differential screening-selected gene aberrative in neuroblastoma) family of bone morphogenetic protein (BMP) antagonists. SOST is produced by the osteocyte and has anti-anabolic effects on bone formation. It is a negative regulator of bone growth that acts through inhibition of Wnt signaling and bone formation.
By Type
Cell Cycle, Chemokines & Cytokines, Immunology, Signal Transduction
Buffer
Lyophilized from a 0.2 um filtered solution of 20mM Tris, 250mM NaCl, pH 8.0. It is not recommended to reconstitute to a concentration less than 100 ug/ml.
Application Note
This recombinant protein can be used for biological assays. For research use only.
NCBI Official Name
sclerostin
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.05 mg
Lieferbar: In stock
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