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BMP 2 Recombinant Protein

ArtNr PRS-96-065-0.02mg
Hersteller ProSci
Menge 0.02 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag Tag Free
Purity >92% as determined by SDS-PAGE.
Sequence Gln 283 - Arg 396
Citations Lai, T.H. et al., (2008) Prostate. 68: 1341-1353.
Kruithof BP,et al. Genesis. 2011 Apr 18. doi: 10.1002/dvg.20757.
Grgurevic L, et al. Biochem Biophys Res Commun. 2011 Apr 29;408(1):25-31.
NCBI BMP2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias BMP2,BMP2A
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
13 kDa
Biological Activity
Corresponding to a specific activity of 20000 IU/mg. The ED50 as determined by the cytolysis of MC3T3-E1 cells is <50 ng/mL.
Background
Human bone morphogenetic protein 2 (BMP2) is also known as human BMP-2, BMP-2, BMP2, BMP 2, h-BMP-2, rh-BMP-2, recombinant human BMP-2, recombinant BMP-2, BMP, is a member of the BMP subgroup belonging to the TGF-b superfamily of structurally related signaling proteins. BMP-2 is a potent osteoinductive cytokine, capable of inducing bone and cartilage formation in association with osteoconductive carriers such as collagen and synthetic hydroxyapatite. In addition to its osteogenic activity, BMP-2 plays an important role in cardiac morphogenesis and is expressed in a variety of tissues including lung, spleen, brain, liver, prostate ovary and small intestine. As implied by its name, BMPs promote and regulate bone development, growth, remodeling and repair, in both prenatal development and postnatal growth of eye, heart, kidney, skin, and other tissues. BMP2 has been demonstrated to potently induce osteoblast differentiation in a variety of cell types, and induce apoptosis in human myeloma cell lines as a novel function.
By Type
Cancer, Cell Cycle, Growth Factors, Signal Transduction, Stem Cell
Buffer
0.1M acetic acid, pH2.0
Application Note
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
bone morphogenetic protein 2
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.02 mg
Lieferbar: In stock
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