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TNFRSF7 Recombinant Protein

TNFRSF7 Recombinant Protein

ArtNr	PRS-96-133-0.2mg
Hersteller	ProSci
Menge	0.2 mg
Kategorie	Oncology Neuroscience Neural Lineage Markers By Cell Type Carcinoma Hematology Lymphoma Melanoma Peptides & Proteins Recombinant Proteins Western Blot Neurodegeneration Markers;Research Area Oncology
Typ	Proteins Recombinant
Format	Lyophilized
Applikationen	WB
Specific against	other
Konjugat/Tag	Fc
Purity	>95% as determined by SDS-PAGE.
Sequence	Thr 21 - Ile 192
Citations	Zhang Z., et al., 2004, Protein Sci. 13:2819-2824. Gravestein L.A., et al., 1998, Eur. J. Immunol. 28:2208-2216. Prasad K.V.S., et al., 1997, Proc. Natl. Acad. Sci. U.S.A. 94:6346-6351.
NCBI	CD27
ECLASS 10.1	32160409
ECLASS 11.0	32160409
UNSPSC	12352202
Alias	CD27, TNFRSF7, S152, S152. LPFS2, T14, Tp55
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Manufacturer - Applications	This recombinant protein can be used for WB. For research use only.
Manufacturer - Conjugate / Tag	C-Fc Tag
Storage Conditions	Lyophilized Protein should be stored at -20°C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20°C or -70°C. Avoid repeated freeze-thaw cycles.
Molecular Weight	45.9 kDa
Biological Activity	Measured by its binding ability in a functional ELISA. Immobilized recombinant human CD27 protein at 2μg/mL (100μl/well) can bind biotinylated human CD70 with a linear range of 0. 25 - 16 ng/mL.
Background	CD Antigen CD27 is also known as Tumor necrosis factor receptor superfamily member 7 (TNFRSF7), which belongs to TNF-receptor superfamily. CD27 / TNFRSF7 is found in most T-lymphocytes. CD27 / TNFRSF7 is required for generation and long-term maintenance of T cell immunity. It binds to ligand CD70, and plays a key role in regulating B-cell activation and immunoglobulin synthesis. This receptor transduces signals that lead to the activation of NF-κB and MAPK8/JNK. CD27 has been shown to interact with SIVA1, TRAF2 and TRAF3.
Buffer	50 mM tris, 100 mM glycine, pH7.5
NCBI Official Name	CD27 molecule
NCBI Organism	Homo sapiens
Disclaimer	Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 0.2 mg

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Lieferung vsl. bis 04.09.2025

Express-Lieferung: 22 Tage sparen

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