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LILRB2 Recombinant Protein

ArtNr PRS-96-515-0.1mg
Hersteller ProSci
Menge 0.1 mg
Kategorie
Typ Proteins Recombinant
Format Lyophilized
Applikationen WB
Specific against other
Konjugat/Tag HIS
Purity >92% as determined by SDS-PAGE.
Sequence Gln 22 - Val 461
Citations Borges L., et al., 1997, J. Immunol. 159:5192-5196.
Fanger N.A., et al., 1998, Eur. J. Immunol. 28:3423-3434.
Shiroishi M., et al., 2003, Proc. Natl. Acad. Sci. U.S.A. 100:8856-8861.
NCBI LILRB2
ECLASS 10.1 32160409
ECLASS 11.0 32160409
UNSPSC 12352202
Alias LILRB2,ILT4,LIR2,MIR10,CD85d
Versandbedingung Raumtemperatur
Lieferbar
Manufacturer - Type
Recombinant Proteins
Shipping Temperature
Room Temp
Storage Conditions
Lyophilized Protein should be stored at -20˚ C or lower for long term storage. Upon reconstitution, working aliquots should be stored at -20˚ C or -70˚ C. Avoid repeated freeze-thaw cycles.
Molecular Weight
48.6 kDa
Biological Activity
Measured by its ability of the immobilized protein to support the adhesion of HSB2 human peripheral blood acute lymphoblastic leukemia cells. When 80000 cells/well are added to LILRB2 coated plates (8. 8μ g/mL with 100μ L/well), > 40% cells will adhere for 1 hour incubation at 37˚ C.
Background
Leukocyte immunoglobulin-like receptor subfamily B member 2 (LILRB2) is also known as CD85 antigen-like family member D (CD85d), Immunoglobulin-like transcript 4 (ILT-4), Monocyte / macrophage immunoglobulin-like receptor 10 (MIR-10), which is a member of the the subfamily B class of LIR receptors. LILRB2 is receptor for class I MHC antigens. LILRB2 recognizes a broad spectrum of HLA-A, HLA-B, HLA-C and HLA-G alleles. LILRB2 competes with CD8A for binding to class I MHC antigens. LILRB2 / CD85d inhibits FCGR1A-mediated phosphorylation of cellular proteins and mobilization of intracellular calcium ions.
Buffer
PBS, pH7.4
Application Note
This recombinant protein can be used for WB. For research use only.
NCBI Official Name
leukocyte immunoglobulin-like receptor, subfamily B (with TM and ITIM domains), member 2
NCBI Organism
Homo sapiens
Disclaimer
Products are intended for laboratory research purposes only and should be used by qualified personnel only. They are not intended for use in humans. ProSci is not liable for damages or injuries resulting from receipt and/or use of ProSci materials. Please refer to the Material Safety Data Sheet (MSDS) for safe storage, handling, and use procedures.
Manufacturer - Species
Human
By Species
Human

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

Menge: 0.1 mg
Lieferbar: In stock
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