ATP6V1E1 Recombinant Protein

This recombinant protein can be used for WB, ELISA, MS.

Store in working aliquots at -70˚ C. Avoid freeze/thaw cycles. When working with proteins care should be taken to keep recombinant protein at a cool and stable temperature.

26 kDa (Calculated)

This protein is a component of vacuolar ATPase (V-ATPase), a multisubunit enzyme that mediates acidification of eukaryotic intracellular organelles. V-ATPase dependent organelle acidification is necessary for such intracellular processes as protein sorting, zymogen activation, and receptor-mediated endocytosis. V-ATPase is comprised of a cytosolic V1 domain and a transmembrane V0 domain. The V1 domain consists of a hexamer of three A and three B subunits plus the C, D, and E subunits. It contains the ATP catalytic site. The protein is known as the E subunit and is found ubiquitously.

Baud, V.; Mears, A. J.; Lamour, V.; Scamps, C.; Duncan, A. M. V.; McDermid, H. E.; Lipinski, M. : The E subunit of vacuolar H(+)-ATPase localizes close to the centromere on human chromosome 22. Hum. Molec. Genet. 3: 335-339, 1994.

529

ATPase, H+ transporting, lysosomal 31kDa, V1 subunit E1

P36543

N/A