COASY Antibody

ArtNr	PRS-14-298-100uL
Hersteller	ProSci
Menge	100 uL
Quantity options	100 uL
Kategorie	Metabolism Cholesterol & Lipid Metabolism Antibodies Immunohistochemistry Western Blot Enzymes Prostaglandin Synthases Primary Antibodies
Typ	Antibody Primary
Format	Liquid
Applikationen	WB, IHC
Specific against	Human (Homo sapiens), Mouse (Murine, Mus musculus), Rat (Rattus norvegicus)
Host	Rabbit
Isotype	IgG
Konjugat/Tag	Unconjugated
NCBI	COASY
ECLASS 10.1	32160702
ECLASS 11.0	32160702
UNSPSC	12352203
Versandbedingung	Gekühlt
Lieferbar
Specificity	Human,Mouse,Rat
Manufacturer - Type	Primary Antibodies
Shipping Temperature	Blue Ice
Storage Conditions	Store at -20˚ C. Avoid freeze / thaw cycles.
Molecular Weight	Observed: 62kDa
Manufacturer - Research Area	Cancer, Signal Transduction
Background	Coenzyme A (CoA) functions as a carrier of acetyl and acyl groups in cells and thus plays an important role in numerous synthetic and degradative metabolic pathways in all organisms. In eukaryotes, CoA and its derivatives are also involved in membrane trafficking and signal transduction. This gene encodes the bifunctional protein coenzyme A synthase (CoAsy) which carries out the last two steps in the biosynthesis of CoA from pantothenic acid (vitamin B5). The phosphopantetheine adenylyltransferase domain of this bifunctional protein catalyzes the conversion of 4'-phosphopantetheine into dephospho-coenzyme A (dpCoA) while its dephospho-CoA kinase domain completes the final step by phosphorylating dpCoA to form CoA. Mutations in this gene are associated with neurodegeneration with brain iron accumulation (NBIA). Alternative splicing results in multiple isoforms.
By Type	Cancer, Signal Transduction
Modifications	None
Purification	Affinity purification
Positive Control 1	LO2
Positive Control 2	293T
Positive Control 3	A-549
Positive Control 4	SKOV3
Positive Control 5	Mouse heart
Positive Control 6	Mouse liver
Concentration	batch dependent
Buffer	PBS with 0.02% sodium azide, 50% glycerol, pH7.3.
Application Note	WB: 1:500 - 1:2000 IHC: 1:100 - 1:200
Immunogen	Recombinant fusion protein containing a sequence corresponding to amino acids 345-564 of human COASY (NP_079509.5).
Clonality	Polyclonal
NCBI Official Name	Coenzyme A synthase
NCBI Organism	Homo sapiens
User Note	Optimal dilutions for each application to be determined by the researcher.
Manufacturer - Additional Names	DPCK, NBIA6, NBP, PCH12, PPAT, UKR1, pOV-2, bifunctional coenzyme A synthase, CoA synthase, bifunctional phosphopantetheine adenylyl transferase/dephospho CoA kinase, nucleotide binding protein, phosphopantetheine adenylyltransferase / dephosphocoenzyme A kinase

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Alle Produkte sind nur für Forschungszwecke bestimmt. Nicht für den menschlichen, tierärztlichen oder therapeutischen Gebrauch.

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Menge: 100 uL

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Lieferung vsl. bis 05.02.2026

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